Propofol vs Propofol + Benzo/Opiates in High Risk Group

• Status: Terminated
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This will be a randomized controlled trial that compares the rates of sedation related complications in high risk patients (ASA greater or equal to 3, BMI greater or equal to 30, those at risk for OSA) undergoing advanced endoscopy procedures with propofol alone compared to propofol in combination with benzodiazepines and opioids.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Treatments: Analgesics, Opioid; Fentanyl; Midazolam; Propofol

Criteria

Inclusion Criteria:

• Ability to provide informed consent

• Age greater than or equal to 18 years

• Presence of at least 1 of the following criteria:

1. ASA class 3 or higher

2. BMI of 30 or greater

3. At risk for OSA (score of 3 or greater on the STOP-BANG screening tool)

Exclusion Criteria:

• drug allergy to Propofol, Benzodiazepines, or Opioids

• patients who received Benzodiazepines or Opioids within 24 hours of the procedure