Dexmedetomidine, was reported to prevent postoperative delirium in elderly patients following
its use in intensive care units. Possible mechanisms included improved quality of sleep and
an inhibitory effect on inflammation. A greater number of studies indicated that propofol has
negative effect on postoperative cognitive function. In this study, we planned to investigate
the influence of these two different sedative drugs on peripheral inflammation induced by
surgery and postoperative cognitive function of patients who will receive hip and knee
arthroplasty.
Phase:
N/A
Details
Lead Sponsor:
The First Affiliated Hospital of Anhui Medical University