Propofol Versus Sevoflurane Recovery After Gynecological Surgery
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
80% of 25 million American who undergo surgery describe moderate to severe pain. The use of
multimodal analgesic techniques can attenuate patient's postoperative pain and several
different medication have been found to be effective. Pain can significantly affect patient's
quality of recovery after surgery. Volatile anesthetics can increase sensitivity to pain at
the low concentrations present on emergence from anesthesia. Propofol may have analgesic
effect at sedative doses. The effects of propofol,when used for anesthesia maintenance, on
postoperative pain have demonstrated controversial results with some investigators showing a
potential benefit whereas others have not shown any benefit. Propofol for maintenance of
anesthesia has been advocated as an strategy for high risk patients even though it has shown
controversial results on reduction of Post operative nausea and vomiting. A comparison of
propofol vs.volatile anesthetic in regards to the time required by patients to meet discharge
criteria has also shown conflicting results.The QOR 40 is a validated instrument that has
been specifically developed to evaluate patients recovery after anesthesia and surgery.
The purpose of this study is to compare the effects of maintenance of anesthesia with two
agents (Propofol and Sevoflurane) on quality of recovery after ambulatory surgery
Significance: the results of this study can lead to the discovery of an anesthesia technique
that is associated with a better recovery for patients after ambulatory surgery.
Research question is: do patients anesthetized with propofol have a better quality of
recovery after ambulatory anesthesia than patients anesthetized with Sevoflurane? The
hypothesis: patients anesthetized with propofol will have better quality of recovery than
patients anesthetized with Sevoflurane after ambulatory surgery.