Overview

Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia

Status:
Completed
Trial end date:
2010-05-01
Target enrollment:
0
Participant gender:
All
Summary
It is unclear whether a topical pharyngeal anesthesia adds any benefit to the upper gastrointestinal endoscopy under a propofol sedation. We hypothesize that a topical pharyngeal anesthesia does not ease the upper gastrointestinal endoscopy under propofol sedation. The aim of this study is therefore to quantify the impact of a topical pharyngeal anesthesia to the upper gastrointestinal endoscopy in patients sedated with propofol. Patients will be randomized to receive a topical pharyngeal spray containing either an anesthetic drug (lidocaine 10%) or a placebo. Thereafter the upper endoscopy will be conducted in its standard manner.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University Hospital, Basel, Switzerland
Treatments:
Anesthetics
Lidocaine
Pharmaceutical Solutions
Propofol
Criteria
Inclusion Criteria:

- Scheduled diagnostic upper endoscopy

- Wish to be sedated

- ASA class I - III

- Signed informed consent

Exclusion Criteria:

- Emergency medical examinations

- Therapeutic Endoscopy

- ASA class IV

- Pregnancy

- Known allergy to propofol or lidocaine