Prophylaxy of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgery
Status:
Unknown status
Trial end date:
2018-01-31
Target enrollment:
Participant gender:
Summary
Postoperative nausea and vomiting (PONV) is one of the most commonly reported adverse effects
of anesthesia. The general incidence of vomiting is approximately 30%, nausea at 50% and the
PONV rate can go up to 80% in high-risk patients without prophylaxis. Prevention of these
episodes in high-risk patients improves satisfaction and well-being rates. Therefore, it
becomes important the adequate control of PONV, aiming at the satisfaction of the patient
with the procedure, lower costs for the health system as well as reduction of complications
in the postoperative period. This study aims to evaluate the association of gabapentin or
pregabalin with dexamethasone in reducing the incidence of PONV in high-risk patients
undergoing laparoscopic surgeries in the first 48 hours postoperatively as well as to assess
side effects.
Phase:
N/A
Details
Lead Sponsor:
Faculdade de Ciências Médicas da Santa Casa de São Paulo