Prophylaxis of Postoperative Nausea and Vomiting After Cardiac Surgery

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To investigate the role of postoperative nausea and vomiting risk factors assessment after cardiac surgery. We designed a randomized controlled study comparing standard care (no risk factor assessment and no intervention) with prophylaxis of postoperative nausea and vomiting after cardiac surgery in high risk patients. Prophylaxis of postoperative nausea and vomiting by betamethasone (4mg) and/or droperidol (0.625mg) immediately after cardiac surgery, depending on risk factors (if risk score is over 2) in the intervention arm.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hôpital Privé de Parly II - Le Chesnay
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate; Droperidol

Criteria

Inclusion Criteria:

• Non emergent cardiac surgery

• Age > 18 years

• Affiliation to French Social Security

• Approval of participation to the study

Exclusion Criteria:

• Pregnancy

• Contra indication to antiemetics

• Chronic usage of antiemetics

• Emergent or complicated surgery