Prophylaxis for Aspiration of Gastric Contents.

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Effect of orally administered two equal and consecutive doses of proton pump inhibitors, omeprazole, lansoprazole, esomeprazole , rabeprazole and pantoprazole and Histamine 2 receptor antagonists cimetidine, ranitidine,famotidine,nizatidine and lafutidine without and with a prokinetic agents domperidone, metoclopramide and erythromycin on intragastric pH, volume and bile refluxate.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: King Saud University
• Treatments: Cimetidine; Dexlansoprazole; Domperidone; Esomeprazole; Famotidine; Lafutidine; Lansoprazole; Metoclopramide; Nizatidine; Omeprazole; Pantoprazole; Rabeprazole; Ranitidine; Ranitidine bismuth citrate

Criteria

Inclusion Criteria: ASA I and II aged 15-70 years

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Exclusion Criteria:

Patients with upper gastrointestinal disorders, Body mass index above 35 kg/m2, Receiving medicines known to effect the secretory and or motor functions of stomach, Had undergone surgery on stomach, With difficult intubation Intestinal obstruction, Partuients and Diabetes

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