Prophylactic vs Therapeutic Anticoagulation in Symptomatic Isolated Distal Deep Vein Thrombosis
Status:
Recruiting
Trial end date:
2023-09-09
Target enrollment:
Participant gender:
Summary
The efficacy and safety of anticoagulant treatment is not established for patients with acute
symptomatic isolated distal deep vein thrombosis (IDDVT). The latest Antithrombotic Therapy
for VTE Disease Guideline suggested using the same anticoagulation as for patients with acute
proximal DVT in patients with acute IDDVT. However, a single-center retrospective cohort
study found therapeutic anticoagulation was associated with an increase risk of bleeding.
Thus, this study aimed to assess the short-term risk of recurrent venous thrombotic events
and bleeding events in patients with a first acute symptomatic IDDVT of the leg treated with
prophylactic or therapeutic anticoagulant therapy with rivaroxaban.