Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies
Status:
Recruiting
Trial end date:
2022-03-31
Target enrollment:
Participant gender:
Summary
This is a Double-blinded randomized placebo-controlled trial based at Eastern Virginia
Medical School. Subjects who are identified in clinic having menorrhagia or abnormal Uterine
bleeding (AUB) due to uterine fibroids and meet inclusion criteria based on the ultrasound
(US) or Magnetic Resonance Imaging (MRI), aged 18-45 undergoing laparoscopic or Robotic
assisted myomectomies. A total of 50 women in each arm of the study with symptomatic
fibroids. Patients will be randomized to receive a single IV bolus injection of TXA 30mg/kg
in 50ml of normal saline (intervention group) versus an IV bolus injection of normal saline
of equivalent volume (placebo group) 15 minutes prior to initial surgical incision.