Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.
Status:
Recruiting
Trial end date:
2025-06-01
Target enrollment:
Participant gender:
Summary
This is a phase III randomized, multicenter study with two different arm:
- experimental: prophylactic surgery plus HIPEC CO2 performed with mitomycin
- comparator: standard surgery Adjuvant treatment after surgery is mandatory except for
documented cases of non-eligibility.
Patient will be randomized in a 1:1 ratio. Randomization will be done during surgery if the
total resection of tumour will be reached and will use a stratification procedure based on
center
Phase:
N/A
Details
Lead Sponsor:
Mario Negri Institute for Pharmacological Research