Prophylactic Olanzapine Versus Placebo for Prevention of Postoperative Delirium After Joint Replacement Surgery

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: All

Summary

In this study we wanted to determine if perioperative administration of olanzapine prior to knee or hip replacement surgery in high risk patients would prevent the onset of postoperative delirium.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The New England Baptist Hospital
• Treatments: Olanzapine

Criteria

Inclusion Criteria:

• High risk for delirium age > 65 history of delirium medical comorbidities ability to give informed consent

Exclusion Criteria:

• Dementia Alcohol abuse Current use of an antipsychotic Allergy to olanzapine