Overview

Prophylactic Norepinephrine Infusion Combined With Colloid Coloading for Postspinal Anesthesia Hypotension

Status:
Not yet recruiting
Trial end date:
2022-10-31
Target enrollment:
0
Participant gender:
Female
Summary
The purpose of this study is to investigate the suitable infusion dose of prophylactic norepinephrine infusion combined with 6% Hydroxyethyl starch (130/0.4) coload for post-spinal anesthesia hypotension in patients undergoing cesarean section.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
General Hospital of Ningxia Medical University
Treatments:
Norepinephrine
Vasoconstrictor Agents
Criteria
Criteria: Inclusion Criteria:

- 18-40 years

- Primipara or multipara

- Singleton pregnancy ≥ 37 weeks

- American Society of Anesthesiologists physical status classification I to II

- Scheduled for elective cesarean section under spinal anesthesia

Exclusion Criteria:

- Body height < 150 cm

- Body weight > 100 kg or body mass index (BMI) ≥ 40 kg/m2

- Eclampsia or chronic hypertension or baseline blood pressure ≥ 160mmHg

- Hemoglobin < 7g/dl

- Coagulation or renal function disorders

- Known allergy to hydroxyethyl starch

- Fetal distress, or known fetal developmental anomaly