Overview

Prophylactic Gabapentin for Taxane-Induced Arthralgia and Myalgia Syndrome in Breast Cancer Patients Undergoing Adjuvant Chemotherapy

Status:
Unknown status

Trial end date:
2020-06-30

Target enrollment:

Participant gender:

Summary

Taxane-induced arthralgia and myalgia syndrome (TAMS) is one of the most common side effects of taxane chemotherapy. This prospective randomized controlled trial will evaluate the efficacy of gabapentin administered prophylactically on days -2 to +5 during the taxane-portion of chemotherapy for adjuvant breast cancer patients on reducing TAMS. This will be compared to observation alone.

Phase:

Phase 2/Phase 3

Details

Lead Sponsor:

British Columbia Cancer Agency

Treatments:

Gabapentin
gamma-Aminobutyric Acid
Taxane