Prophylactic Antibiotics on Urethral Catheter Withdrawal

• Status: Completed
• Trial end date: 2007-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Urinary-tract infection (UTI) is the most common type of hospital-acquired infection (30% of all). The purpose of this study is to determine whether antibiotic prophylaxis for urinary catheter removal is useful at preventing catheter-associated urinary-tract infection.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: St. Antonius Hospital
• Treatments: Anti-Bacterial Agents; Ciprofloxacin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

Criteria

Inclusion Criteria:

• Urethral catheter in situ for at least 3 days (72h)

Exclusion Criteria:

• Pregnancy

• Impaired renal or hepatic function (serum creatinine > 150 mmol/l, serum transaminases > 75 IU/l)

• Fever

• Symptomatic urinary tract infection

• Antibiotic use ≤ 48 hours before urinary catheter removal

• Allergy to trimethoprim-sulfamethoxazole or ciprofloxacin

• Urologic pathology