Overview

Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

Status:
Recruiting
Trial end date:
2025-08-15
Target enrollment:
Participant gender:
Summary
This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help researchers to predict patient complications and identify better ways to manage these complications.
Phase:
Phase 4
Details
Lead Sponsor:
Roswell Park Cancer Institute
Collaborator:
National Cancer Institute (NCI)
Treatments:
Clindamycin
Ertapenem
Levofloxacin
Nitrofurantoin
Ofloxacin
Sulfamethoxazole
Trimethoprim
Trimethoprim, Sulfamethoxazole Drug Combination