Prophylactic Antibiotic Treatment of Patients With Chronic Obstructive Lung Disease (COLD)
Status:
Unknown status
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to investigate, in patients with moderate to severe chronic
obstructive lung disease, whether intermittent antibiotic treatment leads to:
- A slower rate of decline in forced expiratory volume in one second (FEV1);
- A reduction in the frequency and severity of exacerbations;
- Fewer hospital admissions for chronic obstructive pulmonary disease (COPD);
- Lower mortality;
- An improved quality of life as compared to a group of placebo treated patients.