Overview

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Status:
Not yet recruiting
Trial end date:
2027-12-01
Target enrollment:
0
Participant gender:
All
Summary
This prospective randomized clinical trial will compare outcomes between patients treated primarily with a prophylactic antibiotic coated nail and those treated with traditional standard of care intramedullary (IM) nailing.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Wake Forest University Health Sciences
Treatments:
Anti-Bacterial Agents
Gentamicins
Tobramycin
Vancomycin
Criteria
Inclusion Criteria:

- Patients 18 years or older

- Gustillo Type II or III open tibia fracture requiring definitive fixation with
intramedullary nail

Exclusion Criteria:

- Less than 18 years of age

- Allergy to vancomycin, tobramycin, or gentamicin

- Unable to speak English or Spanish,

- Pregnant and lactating women

- Prisoner

- Unable to follow up for 12 months