Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
The use of topical retinoids is a mainstay and basis of early acne treatment to prevent the
progression to inflammatory lesions. Post oral isotretinoin, it is not uncommon for
non-inflammatory papules and comedones to recur. However, there has been no formal study to
look at the prevention of recurrence of these acne lesions post isotretinoin in a long term
basis. This may enhance the therapeutic options for post isotretinoin patients in order to
prevent recurrence of their disease.
Hypothesis Tretinoin microsphere 0.04% will prevent recurrence of acne lesions.