Promethazine vs. Lorazepam for Treatment of Vertigo

• Status: Completed
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study was a prospective, randomized, double-blind, parallel group clinical trial designed to compare the efficacy of intravenous (IV) promethazine and lorazepam for the treatment of peripheral vertigo in Emergency Department setting.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shahid Beheshti University of Medical Sciences
• Treatments: Diphenhydramine; Lorazepam; Promethazine

Criteria

Inclusion Criteria:

• Aged 18 years or older

• Background history of positional vertigo

Exclusion Criteria:

• Unable to provide informed consent

• Pregnant or possibly pregnant

• Known allergy to study medications

• Use of antiemetic agents in the previous 24 hours

• Evidence of drug-induced vertigo or orthostatic hypotension

• Central pathologies/central origin for vertigo