Overview Prolonging Remission in Depressed Elderly (PRIDE) Status: Completed Trial end date: 2016-03-01 Target enrollment: Participant gender: Summary This study will determine whether medications alone or medications and electroconvulsive therapy (ECT) work best to prevent depressive relapse and to improve quality of life for older people with severe mood disorders. Phase: Phase 4 Details Lead Sponsor: Icahn School of Medicine at Mount SinaiCollaborator: National Institute of Mental Health (NIMH)Treatments: Lithium CarbonateVenlafaxine Hydrochloride