Overview

Progression of HIV-Disease Under Low Dose Corticosteroids

Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
There has been reports that low dose prednisolone stabilizes CD4-counts in HIV infected individuals. However, until now, there are no prospective randomized studies on the use of corticosteroids in latent HIV disease. Furthermore, low dose prednisolone (5 mg/d) is not sufficient tested for the risks and benefit for HIV patients especially for those living in poor settings with a higher risk of infections. This study will assess the benefit and the safety profile for low dose prednisolone therapy for patients in a region with limited resources and high prevalence of infections.
Phase:
Phase 2
Details
Lead Sponsor:
Medical Mission Institute, Germany
Collaborators:
Action Medeor
Evangelisches Studienwerk Villigst, Germany
Georg Friedrich Rexroth Stiftung, Lohr, Germany
German Leprosy and Tuberculosis Relief Association
University of Wuerzburg
Treatments:
Methylprednisolone
Methylprednisolone acetate
Methylprednisolone Hemisuccinate
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate