Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Third Trimester Medical Termination of Pregnancy Analgesia : a Randomized Study. (PCEA-IMG)

• Status: Completed
• Trial end date: 2018-12-11
• Target enrollment: 0
• Participant gender: Female

Summary

Background : Recently, delivery of local anaesthetics via Programmed Intermittent Epidural Bolus (PIEB) has been shown to improve labour epidural analgesia compared to delivery via Continuous Epidural Infusion (CEI).

Purpose : However, the superiority of PIEB compared to CEI has not been investigated for third trimester voluntary termination of pregnancy.

We hypothesized that PIEB administration would result in a better degree of satisfaction of the patients compared with CEI for third trimester legally induced abortion analgesia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Limoges
• Treatments: Bupivacaine; Clonidine; Levobupivacaine; Sufentanil

Criteria

Inclusion Criteria:

• age ≥ 18 years

• ASA 1 or 2 (healthy women)

• pregnancy at third trimester

• willingness of voluntary interrupt the pregnancy

• women affiliated to french health social system

• written informed consent from every patient

Exclusion Criteria:

• contraindications to epidural analgesia

• opioids consumption within the last 24 hours

• patient's unwillingness

• inability to comprehend or comply with the procedure