Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)
Status:
Terminated
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Progestin-induced endometrial shedding (PIES) followed by clomiphene citrate is fertility
treatment of choice in anovulatory women with polycystic ovary syndrome (PCOS). However, some
preliminary data suggest that skipping PIES could result in a higher live birth rate. The
investigators are performing the first randomized controlled trial to find out if skipping
the use of progestin during fertility treatment of anovulatory PCOS women is associated with
improved pregnancy and live birth rates compared to the traditional approach of using
progestin prior to use of clomiphene citrate.