Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
The use of procedural sedation and analgesia (PSA) to accomplish painful procedures in the
emergency department (ED) has become a standard of practice over the last decade. Substantial
variance exists regarding usage of medication for PSA, and many anesthetic agents have been
proposed for this use.
To our knowledge no head to head study compared the clinical effectiveness, safety profile
and amnestic properties of midazolam/ketamine vs. propofol regimens for PSA in the adult ED
setting.
This prospective randomized trail can will help to evaluate the effectiveness and safety
profile of Midazolam/katamine regimen for ED PSA in adults and will contribute to the
discussion regarding propofol roll in the ED.