Overview

Primary Systemic Therapy in Operable/Locally Advanced Breast Cancer

Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to find out what effects taking the drug bevacizumab together with two chemotherapeutic agents, docetaxel and cyclophosphamide followed by doxorubicin alone before surgery will on breast cancer. Bevacizumab will be given for twelve weeks in combination with chemotherapy then it ill be held during the administration of doxorubicin. Twenty-eight to fifty-six days after undergoing surgery, all patients will receive nine three-weekly infusions of bevacizumab.
Phase:
Phase 2
Details
Lead Sponsor:
University of Arkansas
Collaborator:
Genentech, Inc.
Treatments:
Bevacizumab
Cyclophosphamide
Docetaxel