Overview

Primary Prophylaxis of Gastric Variceal Bleed

Status:
Unknown status
Trial end date:
2020-07-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to study the efficacy of endoscopic cyanoacrylate injection versus balloon-occluded retrograde transvenous obliteration in the prevention of gastric variceal bleeding.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
West China Hospital
Treatments:
Polidocanol
Criteria
Inclusion Criteria:

1. Cirrhosis

2. Patients with high risk gastric varices (GOV2 or IGV1)

3. Presence of gastrorenal shunt

Exclusion Criteria:

1. Acute bleed or past history of bleed from gastric varices

2. Previous treatment of gastric varices.

3. Non-cirrhotic portal hypertension

4. Contraindications to cyanoacrylate injection or BRTO

5. Portal cavernoma

6. Hepatorenal syndrome

7. Proven malignancy including hepatocellular carcinoma

8. End-stage renal disease under renal replacement therapy;

9. Cardiorespiratory failure

10. Pregnancy or patients not giving informed consent for endoscopic procedures