Primary Hyperparathyroidism: Does a Systematic Treatment Improve the Calcium and Bone Metabolism After Surgery?
Status:
Unknown status
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
Primary Hyperparathyroidism (pHPT) increases bone turnover and resorption and thus calcium
efflux out of bone. After successful surgical treatment of pHPT, bone takes up calcium again
which may result in secondary hyperparathyroidism or even "hungry bone syndrome". Until today
there are no studies about this problem helping to develop recommendations or guidelines how
to prevent these symptoms.
Study hypothesis: Calcium and vitamin D intake after surgery for PHPT protects the bone by
keeping PTH in the normal range (less secondary, reactive hyperparathyroidism), prevents
hungry bone- syndrome and improve bone-turnover markers (osteoporosis protection).
Phase:
Phase 2
Details
Lead Sponsor:
Medical University of Vienna
Treatments:
Calcium Calcium, Dietary Ergocalciferols Vitamin D Vitamins