Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers
Status:
Completed
Trial end date:
2015-10-01
Target enrollment:
Participant gender:
Summary
In this study, the investigators are interested to know if lower doses of Primaquine together
with dihydroartemisinin-piperaquine can produce a similar effect of clearing both sexual and
asexual parasites in asymptomatic carriers compared to the recommended dose of primaquine but
with a decreased risk of haemolysis.
Children (> 1 year) and adults with normal Glucose-6-phosphate dehydrogenase enzyme levels
but with asexual Plasmodium falciparum parasites on the day of screening will be invited to
take part in this study.
Phase:
Phase 3
Details
Lead Sponsor:
London School of Hygiene and Tropical Medicine Medical Research Council Unit, The Gambia