Overview

Prevention of Thrombosis Recurrence in Patients With Low Circulating Levels of Antithrombin.

Status:
Unknown status

Trial end date:
1969-12-31

Target enrollment:
0

Participant gender:
All

Summary

The aim of this study is to estimate the incidence of spontaneous and provoked recurrent VTE and the bleeding events during a 10-year follow-up in subjects experiencing a first VTE stratified according to % AT levels and to treatment schedule (long-term vs 6-12 months oral anticoagulation+transient prophylaxis during high risk periods)

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Federico II University

Treatments:

Antithrombin III
Antithrombins

Criteria

Inclusion Criteria:

- Recent (<3 months) First VTE event

Exclusion Criteria:

- missing data during the follow-up; contraindications to or lack of compliance to oral
anticoagulation (OAT), lack of informed consent; history of previous VTE event;
indication for continuous oral anticoagulation (e.g., an artificial heart valve or
chronic atrial fibrillation); events occurring during pregnancy, malignancy,
puerperium, oral contraceptive intake, hormone replacement therapy; deficiencies of
Prot. C and Prot S or combined inhibitor deficiencies.