Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Duodenal carcinomas are the leading cause of mortality in patients with Familial Adenomatous
Polyposis (FAP) who underwent prophylactic colorectal surgery. The purpose of this study is
to determine wether celecoxib combined with ursodeoxycholic acid is an effective
chemoprevention strategy to influence the progression of duodenal adenomas to carcinomas in
patients with FAP.