Prevention of Preterm Birth in Pregnant Women at Risk Identified by Ultrasound: Evaluation of Two Treatment Strategies
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
The preterm birth is considered as a main problem in the modern obstetrics, being the
responsible of greatest of 50% neonatal morbimortality and heavy costs. Despite the
significant medical advances, the rate of prematurity has not declined over the past 40 years
and even continues to rise in the developed countries. In order to decrease the prematurity
is necessary that two premises: to identify the pregnant women at risk of preterm birth, and
dispose of useful measures aimed at prolonging the pregnancy and therefore avoid preterm
delivery. The investigators propose a clinical trial with the objective to identify effective
strategies to reduce the premature birth (34 weeks and earlier) rate in the population of
pregnant women at risk for premature birth, which will be identified by ultrasound during the
second trimester of their pregnancy.
The investigators intend to compare two accepted strategies: administration of progesterone
(vaginally) or the placement of vaginal pessaries. These 2 strategies are affordable, easy to
apply, and they present very few maternal-fetal secondary effects.