Prevention of Post-traumatic Seizures With Levetiracetam
Status:
Terminated
Trial end date:
2010-05-01
Target enrollment:
Participant gender:
Summary
Post-traumatic seizures can appear frequently after a severe traumatic brain injury. Two
types of seizures are usually identified: early seizures during the week following the trauma
and late epilepsy afterward. Several antiepileptic drugs are usually used to prevent early
seizures but no treatment has demonstrated any preventive effect against late epilepsy.
Levetiracetam is an antiepileptic drug usually used for the treatment of epileptic patients
and has pharmacologic properties that could also be interesting for the prevention of
post-traumatic epilepsy.