Prevention of Periprosthetic Bone Loss After Total Hip Replacement by Annual Bisphosphonate Therapy
Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Periprosthetic bone loss caused by stress-shielding effect, a phenomenon of bone atrophy
under mechanical unloading after THR implantation, further compromises the longevity of
implant. The prospective randomized study is aimed to investigate the periprosthetic bone
loss after primary total hip replacements.