Prevention of Locally Advanced NSCLC Radiotherapy Pneumonia by Inhaling Beclomethasone Propionate
Status:
Unknown status
Trial end date:
2020-12-30
Target enrollment:
Participant gender:
Summary
Radical radiotherapy is the main treatment of locally advanced lung cancer, and radiation
pneumonia is the main toxic effects of radiotherapy. Among them, the fatality rate of severe
radiation pneumonia can reach 50%, which is very harmful to tumor patients. At present, the
treatment mode of radiation pneumonia is very few, and the therapeutic effect is poor. The
prevention of radiation pneumonitis may be the best way to reduce the number of patients with
Post-radiotherapy pneumonia. Previous small clinical studies have shown that the incidence of
radiation pneumonia in inhaled beclomethasone group (2 /28) was significantly lower than that
in oral prednisone group (8 /29) during radiotherapy. The purpose of this study was to
compare the efficacy and safety of radiotherapy between the therapeutic group (inhaled
beclomethasone during radiotherapy) and the control radiotherapy group (patients received
radiotherapy only), especially the incidence of radiation-induced pneumonia within half a
year.