Prevention of Hepatitis B Virus Vertical Transmission by Serovaccination and Tenofovir During Pregnancy
Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
The risk of vertical HBV transmission is related to HBV DNA level in pregnant women, around
30% in women with HBV DNA above 1, 000 000 I.U/mL despite serovaccination of newborns. Using
tenofovir DF during the last trimester of pregnancy allows to reduce the risk, but data from
Western countries are needed.