Prevention of Coronary Slow Flow or No-Reflow During PPCI in Patients With Acute STEMI
Status:
Unknown status
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
Primary percutaneous coronary intervention (PPCI) is the gold standard of treatment of ST
segment elevation myocardial infarction (STEMI).Slow flow / no-reflow phenomenon following
PPCI in STEMI patients has been a serious and common complication that closely related to the
incidence of major adverse cardiovascular events (MACE) and affected patients' prognosis. No
reflow is a multi-factorial phenomenon. And its preventive and therapeutic effects are not
satisfactory. This prospective randomized controlled study aimed to compare favorable effects
of Nitroprusside versus Tirofiban on the prevention of slow flow / no-reflow phenomenon
during PPCI.
Phase:
N/A
Details
Lead Sponsor:
The First Affiliated Hospital of Zhengzhou University
Collaborators:
Anyang Regional Hospital First Affiliated Hospital of Xinjiang Medical University Huaihe Hospital of Henan University Jincheng People's Hospital Jincheng People’s Hospital Kaifeng Central Hospital Lushan People's Hospital Lushan People’s Hospital Nanyang Central Hospital People's Hospital of Zhengzhou University Puyang Oil Field General Hospital Puyang Oilfield General Hospital Puyang People's Hospital Shenma Medical Group General Hospital The 99th Central Hospital of the People's Liberation Army The First Affiliated Hospital of Henan University of Science and Technology The First Affiliated Hospital of Xinxiang Medical University The First People's Hospital of Shangqiu The First People's Hospital of Xinmi The First People's Hospital of Zhumadian The Peoples' Hospital of Jiaozuo City The second people's Hospital of Jiyuan The Second People's Hospital of Pingdingshan Xinyang Central Hospital Yanshi People's Hospital Yanshi People’s Hospital Yellow River Sanmenxia hospital Zhengzhou Cardiovascular Hospital Zhengzhou Central Hospital Zhengzhou First People's Hospital Zhengzhou First People’s Hospital Zhoukou Central Hospital Zhumadian Central Hospital