Prevention of Contrast Induced Nephropathy in Oncology Patients With Sodium Bicarbonate
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
Contrast induced nephropathy is a rising cause of acute renal failure in all patients. A
study published in JAMA 2004, show a superiority of a hydratation with sodium bicarbonate in
comparison with the same volume hydratation with sodium bicarbonate. The investigators will
try following the original protocol making 2 randomized groups of patients, with cancer
diagnosis, >18 years old, with a GFR <60 and >30 ml/min/1,73m2 by MDRD formula and/or
diabetic patients. In the group 1 the patients will receive a solution with 154 mEq/L of a
sodium bicarbonate, 3 cc/Kg/h at 1 hour before the injection of contrast and 1 cc/Kg/h during
and 6 hours before the injection. The primary end point will be the rise of 25% or more in
creatinine or dialysis needed.