Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures
Status:
Completed
Trial end date:
2004-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the efficacy of graft pretreatment with the E2F
decoy, CGT003, as compared to placebo, on the occurrence of graft failure among patients who
receive autogenous vein grafts to treat chronic critical limb ischemia; on the occurrence of
clinically significant graft stenosis (more than or equal to 70%); and on the incidence of
critical limb ischemia (e.g., gangrene, non-healing ischemic ulcers or ischemic rest pain).