Preventing the Inflammatory Response to Experimentally-induced Insomnia Symptoms
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to learn about the effects of sleep disruption (two days in
a row where sleep is shortened and disrupted) on inflammation, mood (how you feel), and pain
processing (your own experiences/perceptions of pain). In this research project, we are
trying to figure out if we can change the effects of sleep disruption on inflammation, mood,
and pain. Therefore, we will study whether taking a low-dose aspirin pill every day over 2
weeks can change how we respond to sleep disruption. For example, does the sensitivity to
pain (e.g., how intense the feeling of pain is if we put our hand in very hot or very cold
water) change with sleep disruption, and can low-dose aspirin influence this change. We are
also interested in seeing how inflammation changes in relation to your own perceived
experience of pain.