Preventing contrAst Induced Nephropathy After TranscathEter Aortic Valve Replacement
Status:
Unknown status
Trial end date:
2019-01-01
Target enrollment:
Participant gender:
Summary
Chronic kidney disease (CKD) and (subsequent) acute kidney injury are frequent in patients
undergoing transcatheter aortic valve implantation (TAVI). Moreover, these patients are
easily hypervolemic and susceptible for cardiac decompensation. Prevention of contrast
induced nephropathy (CIN) has not yet been studied in these patients, and evidence on
different strategies is urgently needed. The objective of this study is to evaluate the
efficacy of 250ml 1.4% sodium bicarbonate versus hypotone saline (0.65% sodiumchloride)
hydration prior to TAVI in patients with CKD to prevent CIN.