Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol

• Status: Completed
• Trial end date: 2013-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the incidence and intensity of possible pain on injection as well as patient satisfaction caused by propofol (a lipid based medication); Lusedra (a water based medication); and the drug combination of propofol with lidocaine (a local anesthetic commonly used with propofol injection).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: New York University School of Medicine; NYU Langone Health
• Collaborator: Eisai Inc.
• Treatments: Fospropofol; Lidocaine; Propofol

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) I, II or III.

• Age 18 - 65.

• Both male and female.

• No significant laboratory abnormalities.

Exclusion Criteria:

• Chronic pain patients or patients receiving benzodiazepines or opioids / other analgesics for control of acute pain will be excluded.

• Patients with known allergies to any of the study drugs, or to soybean oil or egg lecithin are excluded.

• Women with a positive pregnancy test reported from pre-surgical testing or their physician's office or who are breast feeding at the time of surgery.

• No emergency patients will be recruited for this study.