Preventing Gastric Glitch With Prucalopride and Buspirone: N-of-1 Clinical Trial

• Status: Completed
• Trial end date: 2022-03-06
• Target enrollment: 0
• Participant gender: Female

Summary

Background: Gastric glitch is a new functional disease characterized by severe and transient epigastric pain occurring after challenges such as drinking alcohol and eating specific foods. Aims: In this N-of-1 trial, we first characterized the clinical and gastric tomographic images of a patient with gastric glitch highly reproducible after alcohol challenging, and then tested the effect of prucalopride and buspirone on the prevention of gastric glitch crises.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidade de Passo Fundo
• Treatments: Buspirone; Prucalopride

Criteria

Inclusion Criteria:

• adult patient suffering from severe gastric pain after ingestion of a small amount of wine

Exclusion Criteria:

• N/A (N-of-1 trial)