Preventing Gastric Glitch With Prucalopride and Buspirone: N-of-1 Clinical Trial
Status:
Completed
Trial end date:
2022-03-06
Target enrollment:
Participant gender:
Summary
Background: Gastric glitch is a new functional disease characterized by severe and transient
epigastric pain occurring after challenges such as drinking alcohol and eating specific
foods. Aims: In this N-of-1 trial, we first characterized the clinical and gastric
tomographic images of a patient with gastric glitch highly reproducible after alcohol
challenging, and then tested the effect of prucalopride and buspirone on the prevention of
gastric glitch crises.