Overview

Preventing Complications in Cleft Palate Repair With Antibiotics

Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to determine the efficacy of administering a single dose of preoperative antibiotics to prevent complications in patients undergoing primary closure of a cleft secondary palate. Secondary objective of this study is to evaluate the effects of preoperative antibiotics administered on post operative outcome following primary closure of cleft secondary palate. The study aims to assess the efficacy of prophylactic antibiotics in cleft surgery to - decrease the incidence of surgical sight infections - speed the progression of postoperative healing - improve the final quality of wound healing achieved - decrease the rate of palatal fistula formation
Phase:
Phase 2
Details
Lead Sponsor:
Children's Hospital of Pittsburgh
Joseph Losee
Treatments:
Ampicillin
Anti-Bacterial Agents
Antibiotics, Antitubercular
Pharmaceutical Solutions
Sulbactam
Sultamicillin