Prevacid vs Lifestyle Modifications for the Treatment of LPR
Status:
Unknown status
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate changes in scores on the Reflux Finding Score and
Reflux Symptom Index over a 24 week period. To enroll subjects must score at least a 13 on
the Reflux Symptom Index and at least a 5 on the Reflux Finding Score. All subjects will
receive education on lifestyle modifications with a nutritionist and exercise trainer. All
subjects will be expected to comply with lifestyle modifications for the entire study period
of 24 weeks. Half of all subjects will receive Prevacid 30mg BID and half will receive
placebo BID for 24 weeks. Subjects will have 4 office visits over 24 weeks and weekly
contacts with the study staff to assess Reflux Symptom Index and any health or medication
changes.