Overview

Preoperative i.v. Iron Substitution in Patients With Colon Cancer

Status:
Recruiting
Trial end date:
2024-12-31
Target enrollment:
0
Participant gender:
All
Summary
About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb <130, female Hb <120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Helsinki University Central Hospital
Criteria
Inclusion Criteria:

- Age> 18 years

- Dg: Colon ca

- The planned measure: the colon resection

- Men: Hb <130, women: Hb <120 and iron deficiency (elevated TfR, low TrFesat or low
ferritin)

Exclusion Criteria:

- hyperreactivity for Ferinject

- haemochromatosis

- refusal for participation