Preoperative Topic Diclofenac as a Prevention of Postoperative Macular Edema in Patients With Diabetic Retinopathy

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Diabetes has many negative effects on patients' general health. Among many other consequences it speeds up the cataract formation and that is why diabetic patients need cataract surgery very often. The known side effect of cataract surgery even in otherwise healthy patients is postoperative edema of the back of the eye (what causes decrease of vision), which has greater incidence especially in patients who have diabetic eye problems. The cause of that might be the intraocular inflammation which was previously demonstrated to be significantly more prominent in patients with untreated diabetic eye problems. Therefore we will examine if the 7 day use of anti-inflammatory eye drops prior to the cataract surgery prevent the formation of the edema of the back of the eye.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eye Clinic Medic Zuljan Jukic
• Collaborators: Clinical Hospital Center, Split; University of Zagreb
• Treatments: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ophthalmic Solutions

Criteria

Inclusion Criteria:

• presence of nonproliferative diabetic retinopathy

• presence of the cataract (LOCS 2-3)

Exclusion Criteria:

• other chronic or acute eye diseases

• hypersensitivity to any component of the diclofenac eye-drops patients on oral anticoagulant therapy

• allergy to salycilates