Preoperative Single Glucocorticoid Hip Fracture Hip Fracture Surgery

• Status: Completed
• Trial end date: 2016-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The Study is a double-blinded, randomized, placebo-controlled trials. The Objective is to investigate the effect of single-high-dose glucocorticoid on surgical stress response and postoperative delirium among Elderly hip Fracture Patients undergoing surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hvidovre University Hospital
• Treatments: Glucocorticoids; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Patients undergoing surgery for hip fracture

• Informed signed consent

• Danish speaking

Exclusion Criteria:

• Allergies towards contents of Solu-Medrol

• Insulin dependent diabetes

• Glaucoma

• In treatment for cancer disease

• Positive HIV, Hepatitis b or C status

• Lack of informed consent (eq. Severe dementia, coma, and others)

• Current treatment with systemic glucocorticoids (pr.os or intravenous) Immunoinflammatory disease (Except topical treated skin disease and respiratory disease)

• Current Immunosuppressive treatment

• Unable to participate in CAM-S measurement

• Peptic ulcera