Preoperative Methylprednisolone in Endovascular Aortic Repair

• Status: Completed
• Trial end date: 2013-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Louise de la Motte
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Elective endovascular repair of an asymptomatic abdominal aortic aneurysm.

• Informed signed consent

Exclusion Criteria:

• Positive HIV status, positive hepatitis B or C status

• Immunoinflammatory disease - except topically treated skin disease and respiratory disease.

• Glaucoma

• Gastric or duodenal ulcer

• Systemic fungal infection

• Immunosuppressive treatment

• Current treatment for cancer

• Allergy towards contents of Solu-Medrol

• Alcohol consumption: Men > 21 drinks and women > 14 drinks weekly

• Pregnancy

• Lack of informed signed consent

• Patients where follow up is planned at other location than Rigshospitalet.