Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study
Status:
Terminated
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well combination chemotherapy works in treating patients with
pancreatic cancer before undergoing surgery. Drugs used in chemotherapy, such as irinotecan
hydrochloride, oxaliplatin, leucovorin calcium, and fluorouracil (FOLFIRINOX), work in
different ways to stop the growth of tumor cells, either by killing the cells, by stopping
them from dividing, or by stopping them from spreading. Giving more than one drug
(combination chemotherapy) before surgery may make the tumor smaller and reduce the amount of
normal tissue that needs to be removed.