Preoperative Folfirinox, Radiation Therapy for Resectable Adenocarcinoma of the Pancreas
Status:
Completed
Trial end date:
2019-02-20
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn if a chemotherapy combination called
modified Folfirinox (or mFolfirinox), followed by a combination of gemcitabine and radiation
therapy, followed by surgery, can help to control pancreatic cancer. The safety of this
treatment will also be studied.
mFolfirinox consists of 5-FU, oxaliplatin, and irinotecan. These 3 drugs, along with
gemcitabine, are each designed to block the growth of cancer cells, which may lead to cancer
cell death.